This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in muscular excitation and contraction. Mutations in this gene cause some autosomal recessive forms of Brody disease, characterized by increasing impairment of muscular relaxation during exercise. Alternative splicing results in three transcript variants encoding different isoforms.

推荐稀释比 WB:1/500-1/1000;FC:1/50-1/100;ELISA:1/10000

Western blot analysis of SERCA1 ATPase in C2C12 (1), COS7 (2), Hela (3), K562 (4), and Jurkat (5) cell lysate using SERCA1 ATPase antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。