The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as integration points for multiple biochemical signals and are involved in a wide variety of cellular processes, such as proliferation, differentiation, transcription regulation and development. This kinase is specifically expressed in a subset of neurons in the nervous system and is activated by threonine and tyrosine phosphorylation. Targeted deletion of this gene in mice suggests that it may have a role in stress-induced neuronal apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.

推荐稀释比 WB:1/500-1/1000;ELISA:1/10000

Western blot analysis of JNK3 in HEK293 (1), Hela (2), SK-N-SH (3), MCF-7 (4), Jurkat (5), and C6 (6) cell lysate using JNK3 antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。