PAK2, also known as P21 (CDKN1A)-activated kinase 2. The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, CDC42 and RAC1, and have been implicated in a wide range of biological activities. PAK2 is activated by proteolytic cleavage during caspase-mediated apoptosis, and may play a role in regulating the apoptotic events in the dying cell. PAK2 has been shown to interact with SH3KBP1, CDC42 and Abl gene.

推荐稀释比 WB:1/500-1/1000;IHC:1/100-1/200;IF:1/50-1/200

Western blot analysis of PAK2 in Hela (1), Jurkat (2), A549 (3), HEK293 (4) and K562 (5) cell lysate using PAK2 antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。