This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.

推荐稀释比 WB:1/500-1/1000;IHC:1/100-1/200;FC:1/50-1/100;ELISA:1/10000

Immunohistochemistry analysis of paraffin-embedded human testis tissues using p57 Kip2 antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。