The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue.Tissue specificity: Highly expressed in placenta. Low expression in small intestine, liver and colon.

推荐稀释比 WB:1/500-1/1000;IF:1/50-1/200;ELISA:1/10000

Western blot analysis of ABCG2 in HepG2 (1), Cos7 (2), Jurkat (3) and NIH/3T3 (4) cell lysate using ABCG2 antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。