Isoform large T antigen is a key early protein essential for both driving viral replication and inducing cellular transformation. Plays a role in viral genome replication by driving entry of quiescent cells into the cell cycle and by autoregulating the synthesis of viral early mRNA. Displays highly oncogenic activities by corrupting the host cellular checkpoint mechanisms that guard cell division and the transcription, replication, and repair of DNA.

推荐稀释比 WB:1/500-1/1000;IF:1/50-1/200;IP:1/20

Western blot analysis of SV40 Tantigen in A549, HL-60, U251 lysates using SV40 T Antigen antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。