The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

推荐稀释比 WB:1/500-1/1000;IHC:1/100-1/200;FC:1/50-1/100

Western blot analysis of PDE1B in PC-12 lysates using PDE1B antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。