Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq) Tissue specificity: Expressed in all tissues examined except brain and heart. Highest levels in thymus, bone marrow and peripheral blood.

推荐稀释比 WB:1/500-1/1000;IF:1/50-1/200;ELISA:1/10000

Western blot analysis of RUNX1 in Jurkat cell lysate using RUNX1 antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。