Papilin is an extracellular matrix glycoprotein involved in, thin matrix layers during gastrulation, matrix associated with wandering, phagocytic hemocytes, basement membranes and space-filling matrix during Drosophila development.Determination of its cDNA sequence led to the identification of Caenorhabditis and mammalian papilins. A distinctly conserved 'papilin cassette' of domains at the amino-end of papilins is also the carboxyl-end of the ADAMTS subgroup of secreted, matrix-associated metalloproteinases; this cassette contains one thrombospondin type 1 (TSR) domain, a specific cysteine-rich domain and several partial TSR domains. In vitro, papilin non-competitively inhibits procollagen N-proteinase, an ADAMTS metalloproteinase.

推荐稀释比 WB:1/500-1/1000;IF:1:50/1:200

Western blot analysis of PAPLN in Hela , HepG2 , OCM1 , Raji , Jurkat , NIH/3T3 lysates using PAPLN antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。