This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

推荐稀释比 WB:1/500-1/1000;IHC:1/100-1/200

Western blot analysis of TIE1 in HepG2 lysates using TIE1 antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。