The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit inTinal absorption and promote biliary excretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and inTine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia.

推荐稀释比 WB:1/500-1/1000;IHC:1/100-1/200;FC:1/50-1/100

Western blot analysis of ABCG5 in HL772 , RAJI and Jurkat lysates using ABCG5 antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。