The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined.

推荐稀释比 IF:1/50-1/200

Immunofluorescence analysis of HFE in HepG2 cells using HFE antibody(green). Blue: DRAQ5 fluorescent DNA dye.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。