This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

推荐稀释比 FC:1/50-1/100;ELISA:1/10000

ELISA plate precoated by 2 μg/ml (100 μl/well) Human GITR protein, hFcHis tagged protein can bind Rabbit antiGITR monoclonal antibody in a linear range of 1100 ng/ml.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。