Acts as a transcriptional activator or repressor. Involved in embryonic lens fiber cell development. Recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation. Activates the expression of IL4 in T helper 2 (Th2) cells. Increases T-cell susceptibility to apoptosis by interacting with MYB and decreasing BCL2 expression. Together with PAX6, transactivates strongly the glucagon gene promoter through the G1 element.

推荐稀释比 WB:1/500-1/1000

Western blot analysis of c-Maf in (1) HUVEC lysates; (2) NIH/3T3 lysates; (3) PC-12 lysates using c-Maf antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。