Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG/SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1.

推荐稀释比 FC:1/50-1/100;ELISA:1/10000

Flow Cytometry analysis of Expi293 cells transfected with Human SCF Blue histogram or Expi293 transfected with irrelevant protein Red histogram stained with SCF antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。