This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants.

推荐稀释比 WB:1/500-1/1000;IHC:1/100-1/200;FC:1/50-1/100;ELISA:1/10000

Western blot analysis of C5AR2 in K562 (1),THP-1 (2), and MOLT4 (3) cell lysate using C5AR2 antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。