Catalyzes the phosphorylation of phosphatidylinositol 4-phosphate (PtdIns4P) to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). PtdIns(4,5)P2 is involved in a variety of cellular processes and is the substrate to form phosphatidylinositol 3,4,5-trisphosphate (PtdIns(3,4,5)P3), another second messenger. The majority of PtdIns(4,5)P2 is thought to occur via type I phosphatidylinositol 4-phosphate 5-kinases given the abundance of PtdIns4P.

推荐稀释比 WB:1/500-1/1000;IP:1/20

Western blot analysis of PIP5KI gamma in mouse brain lysates using PIP5K1C antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。