Inhibits IPF1/PDX1 transactivation of established target promoters, such as insulin, may be by recruiting a repressor complex (By similarity). In complex with CUL3, involved in ubiquitination of BMI1, H2AFY and DAXX, and probably also in ubiquitination and proteasomal degradation of Gli2 or Gli3.

推荐稀释比 WB:1/500-1/1000

Western blot analysis of SPOP in MCF-7 lysates using SPOP antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。