Incorporated into fibronectin-containing matrix fibers. May play a role in cell adhesion and migration along protein fibers within the extracellular matrix (ECM). Could be important for certain developmental processes and contribute to the supramolecular organization of ECM architecture, in particular to those of basement membranes. Has been implicated in a role in cellular transformation and tumor invasion, it appears to be a tumor suppressor. May play a role in haemostasis and thrombosis owing to its ability to bind fibrinogen and incorporate into clots. Could play a significant role in modulating the neurotrophic activities of APP, particularly soluble APP.

推荐稀释比 WB:1/500-1/1000;IP:1/20

Western blot analysis of Fibulin 1 in Human placenta, A549, 3T3 lysates using Fibulin 1 antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。