Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells. Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti-apoptotic signaling of PTN and regulation of cell proliferation. Binds to cell-surface target proteins via their chondroitin sulfate groups.Down-regulates PTPRZ1 activity .

推荐稀释比 WB:1/500-1/1000;IP:1/20

Western blot analysis of PTN in U87-MG lysates using PTN antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。