Tyrosine-protein kinase that acts as cell-surface receptor for CSF1 and IL34 and plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. Promotes the release of proinflammatory chemokines in response to IL34 and CSF1, and thereby plays an important role in innate immunity and in inflammatory processes. Plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone and tooth development.

推荐稀释比 WB:1/500-1/1000

Western blot analysis of M-CSF Receptor in K562 lysates using M-CSF Receptor antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。