Involved in DNA damage response; activates kinases ATM, SMC1A and PRKDC by modulating their phosphorylation status following ionizing radiation (IR) stress. Plays a role in regulating mitochondrial function and cell proliferation. Required for protein stability of MTOR and MTOR-related proteins, and cell cycle progress by growth factors.

推荐稀释比 WB:1/500-1/1000;IF:1/50-1/200;IP:1/20

Western blot analysis of BRAT1 in K562 lysates using BRAT1 antibody.

Immunocytochemistry analysis of BRAT1(green) in Hela using BRAT1 antibody,and DAPI(blue)

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。