Cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. Acts as a translational activator. Seems to play an essential role in cold-induced suppression of cell proliferation. Binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. Acts as a translational repressor . Promotes assembly of stress granules (SGs), when overexpressed.

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100;IP:1/20

Western blot analysis of CIRBP in Hela lysates using CIRBP antibody.

Immunohistochemistry analysis of paraffin-embedded Human breast cancer using CIRBP antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。