It has recently been shown that upregulation of LIN28A and LIN28B in primary human tumors and human cancer cell lines is correlated with downregulation of let-7 miRNAs. LIN28 genes are reported to be involved in primordial germ cell development and germ cell malignancy. In addition, allelic variation in LIN28B is associated with regulating the timing of puberty in humans.

推荐稀释比 WB:1/500-1/1000;IF:1/50-1/200;IP:1/50;FC:1/50-1/100

Western blot analysis of Lin28B in K562 lysates using LIN28B antibody.

Immunofluorescence analysis of LIN28B in MCF-7 using Lin28B antibody.

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