This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described.

推荐稀释比 WB:1/500-1/1000

Western blot analysis of POT1 in K562, C6, 3T3 lysates using POT1 antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。