Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins.

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100;IP:1/50;FC:1/50-1/100

Western blot analysis of PAG in Raji lysates using PAG1 antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。