PBEF1: nicotinamide phosphoribosyltransferase. This gene encodes a protein that catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. The protein is an adipokine that is localized to the bloodstream and has various functions, including the promotion of vascular smooth muscle cell maturation and inhibition of neutrophil apoptosis. It also activates insulin receptor and has insulin-mimetic effects, lowering blood glucose and improving insulin sensitivity. The protein is highly expressed in visceral fat and serum levels of the protein correlate with obesity.

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100;IF:1/50-1/200;IP:1/20

Immunocytochemistry analysis of Nampt (green) in U87-MG using Nampt antibody,and DAPI(blue).

Western blot analysis of Visfatin in 3T3, Raw264.7 lysates using Visfatin antibody.

Western blot analysis of Visfatin in Hela, A549, HL-60, U2OS, C6 lysates using Visfatin antibody

Immunohistochemistry analysis of paraffin-embedded Human lung cancer using Visfatin antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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