Calcium/calmodulin-dependent serine/threonine kinase involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and autophagy. Regulates both type I apoptotic and type II autophagic cell death signals, depending on the cellular setting. The former is caspase-dependent, while the latter is caspase-independent and is characterized by the accumulation of autophagic vesicles. Acts as a mediator of anoikis and a suppressor of beta-catenin-dependent anchorage-independent growth of malignant epithelial cells. May play a role in granulocytic maturation. Regulates granulocytic motility by controlling cell spreading and polarization.

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100

Western blot analysis of DAPK2 in rat spleen lysates using DAPK2 antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。