DNA double-strand breaks are generated by ionizing radiation and endogenously produced radicals, and they often are repaired through the RAD52 homologous recombination pathway. The complex possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity, which are provided by MRE11A. RAD50 may be required to bind DNA ends and hold them in close proximity.

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100

Western blot analysis of Mre11 in K562, rat Brain, C6, 3T3, Hela lysates using Mre11 antibody.

Immunohistochemistry analysis of paraffin-embedded Human lung cancer using Mre11 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。