Non-receptor tyrosine-protein kinase that plays a role in many biological processes including regulation of cell growth and survival, cell adhesion, integrin-mediated signaling, cytoskeletal remodeling, cell motility, immune response and axon guidance. Inactive FYN is phosphorylated on its C-terminal tail within the catalytic domain. Following activation by PKA, the protein subsequently associates with PTK2/FAK1, allowing PTK2/FAK1 phosphorylation, activation and targeting to focal adhesions.

推荐稀释比 WB:1/500-1/1000

Western blot analysis of Fyn in U87-MG, 3T3 muscle lysates using FYN antibody.

Western blot analysis of Fyn in rat Brain lysates using Fyn antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。