Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex . As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes .

推荐稀释比 WB:1/500-1/1000

Western blot analysis of WAVE 1 in rat Brain, C6, 3T3, Hela lysates using WAVE 1 antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。