Microtubule-dependent motor required for normal distribution of mitochondria and lysosomes. Can induce formation of neurite-like membrane protrusions in non-neuronal cells in a ZFYVE27-dependent manner . Regulates centrosome and nuclear positioning during mitotic entry. During the G2 phase of the cell cycle in a BICD2-dependent manner, antagonizes dynein function and drives the separation of nuclei and centrosomes (PubMed:20386726). Required for anterograde axonal transportation of MAPK8IP3/JIP3 which is essential for MAPK8IP3/JIP3 function in axon elongation .

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100;IF:1/50-1/200;IP:1/20

Western blot analysis of KIF5B in mouse brain, rat brain lysates using KIF5B antibody.

Western blot analysis of KIF5B in Hela, MCF-7, U251MG, K562 lysates using KIF5B antibody.

Immunohistochemistry analysis of paraffin-embedded Human breast cancer using KIF5B antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Immunocytochemistry analysis of KIF5B (green) in Hela using KIF5B antibody,and DAPI(blue).

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。