Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC5 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.

推荐稀释比 WB:1/500-1/1000;IF:1/50-1/200;IP:1/20

Western blot analysis of PSMC5 in mouse heart lysates using PSMC5 antibody.

Western blot analysis of PSMC5 in C6, Hela lysates using PSMC5 antibody.

Immunocytochemistry analysis of PSMC5(green) in Hela using PSMC5 antibody,and DAPI(blue)

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。