Binds to DNA, at nuclear matrix- or scaffold-associated regions. Thought to recognize the sugar-phosphate structure of double-stranded DNA. Transcription factor controlling nuclear gene expression, by binding to matrix attachment regions (MARs) of DNA and inducing a local chromatin-loop remodeling. Acts as a docking site for several chromatin remodeling enzymes and also by recruiting corepressors (HDACs) or coactivators (HATs) directly to promoters and enhancers.

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100;IF:1/50-1/200

Western blot analysis of SATB2 in HT-1080,Rat brain, Mouse brain lysates using SATB2 antibody.

Western blot analysis of SATB2 in HT1080，Rat brain lysates using SATB2 antibody.

Western blot analysis of SATB2 in Saos2 lysates using SATB2 antibody.

Immunohistochemistry analysis of paraffin-embedded Human stomach cancer using SATB2 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Immunofluorescence analysis of SATB2 in SH-SY5Y using SATB2 antibody.

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