ADCY5 encodes a member (adenylate cyclase 5) of the membrane-bound adenylyl cyclase enzymes. Adenylyl cyclases mediate G protein-coupled receptor signaling through the synthesis of the second messenger cAMP. Activity of the encoded protein is stimulated by the Gs alpha subunit of G protein-coupled receptors and is inhibited by protein kinase A, calcium and Gi alpha subunits. Single nucleotide polymorphisms in this gene may be associated with low birth weight and type 2 diabetes. Alternatively spliced transcript variants that encode different isoforms have been observed for ADCY5.

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100;IF:1/50-1/200;ELISA:1/10000

Western blot analysis of ADCY5/6 in various lysates using ADCY5/6 antibody.

Western blot analysis of ADCY5/6 in COLO205 lysates using A Cyclase V/VI antibody.

Western blot analysis of ADCY5/6 in COLO25 lysates using ADCY5/6 antibody. The lane on the right is blocked with the synthesized peptide.

Western blot analysis of ADCY5/6 in HUVEC lysates using ADCY5/6 antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。