GDNF family receptor alpha-3 is a protein that in humans is encoded by the GFRA3 gene. The protein encoded by this gene is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand, artemin. Widely expressed in adult and fetus which exhibit a similar pattern. Essentially not expressed in the central nervous system, but highly expressed in several sensory and sympathetic ganglia of the peripheral nervous system. Moderate expression in many non-neuronal tissues, particularly those of the digestive and urogenital systems, but high expression in stomach and appendix. Several types of glandular tissues show low expression.

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100

Western blot analysis of GFRA3 in Human fetal kidney, Human brain lysates using GFRA3 antibody

Immunohistochemistry analysis of paraffin-embedded Human colorectal cancer using GFRA3 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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