Integrin alpha-6/beta-4 is a receptor for laminin. It plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling. ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling. ITGA6:ITGB4 binds to IGF2 and this binding is essential for IGF2 signaling.

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100

Western blot analysis of Integrin beta 4 in SW480 lysates using Integrin beta 4 antibody.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。