Menin, the protein product of the MEN1 gene, is a component of the mixed-lineage leukemia protein (MLL)-containing histone methyltransferase complex that facilitates methylation of histone H3 Lys4 to promote transcriptional activation. Menin functions to suppress proliferation of pancreatic islet cells, at least in part through MLL-mediated activation of the p18INK4c (p18) and p27CIP/KIP (p27) cyclin-dependent kinase inhibitor genes.

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100

Western blot analysis of Menin in K562, Hela, A431 and NIH/3T3 lysates using Menin antibody

Immunohistochemistry analysis of paraffin-embedded Human tonsil using Menin antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。