The protein encoded by this gene is an androgen receptor coactivator that forms a complex with protein arginine methyltransferase 5, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins. The encoded protein may be involved in the early stages of prostate cancer, with most of the protein being nuclear-localized in benign cells but cytoplasmic in cancer cells. Several transcript variants encoding different isoforms have been found for this gene.

推荐稀释比 WB:1/500-1/1000;IF:1:50/1:200

Western blot analysis of WDR77 in C6, 3T3 and K562 lysates using WDR77 antibody.

Immunocytochemistry analysis of WDR77 (8A10) in HeLa using WDR77 antibody.

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