Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD1 is a receptor-regulated SMAD (R-SMAD). SMAD1/OAZ1/PSMB4 complex mediates the degradation of the CREBBP/EP300 repressor SNIP1. May act synergistically with SMAD4 and YY1 in bone morphogenetic protein (BMP)-mediated cardiac-specific gene expression.

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100;IF:1/50-1/200

Western blot analysis of Smad1 in HT-1080, HUVEC, mouse C2C12 line and rat liver lysates(from left to right), using SMAD1 antibody. (Center)

Immunofluorescence analysis ofSmad1 in MCF-7 cells using SMAD1 antibody(Center)(green).

Immunohistochemistry analysis of paraffin-embedded H. heart section using SMAD1 antibody (Center).High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Immunohistochemistry analysis of paraffin-embedded H. skeletal muscle section using SMAD1 antibody (Center)with DAB staining.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。