Eukaryotic protein kinases are enzymes that belong to a very extensive family of proteins which share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. This gene encodes an inTinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases. The protein localizes to the inTinal crypt region and is thought to be important in inTinal epithelial cell proliferation and differentiation. Alternative splicing has been observed at this locus and two variants, encoding the same isoform, have been identified.

推荐稀释比 IHC:1/50-1/100

Immunohistochemistry analysis of paraffin-embedded Human brain using ICK antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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