This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence.

推荐稀释比 WB:1/500-1/1000

Western blot analysis of FZD4 in mouse heart lysates using FZD4 antibody diluted at 1:200

-25 ~ -15℃保存，收到货之后有效期1年，避免反复冻融。