The protein encoded by this gene belongs to the class-II aminoacyl-tRNA synthetase family. Aminoacyl-tRNA synthetases play critical roles in mRNA translation by charging tRNAs with their cognate amino acids. The encoded protein is a mitochondrial enzyme that specifically aminoacylates alanyl-tRNA. Mutations in this gene are a cause of combined oxidative phosphorylation deficiency 8. Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100

Western blot analysis of AARS2 in SP20 lysates using AARS2 antibody

Immunohistochemistry analysis of paraffin-embedded Human brain using AARS2 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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