Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway, the p53 pathway and the steroid hormone signaling pathway.

推荐稀释比 WB:1/500-1/1000

Western blot analysis of PIAS1 in Human testis and Human placenta lysates using PIAS1 antibody.

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