This gene is a member of the glutathione S-transferase (GSTs) super-family which encodes multifunctional enzymes important in the detoxification of electrophilic molecules, including carcinogens, mutagens, and several therapeutic drugs, by conjugation with glutathione. This enzyme catalyzes the conversion of maleylacetoacetate to fumarylacetoacatate, which is one of the steps in the phenylalanine/tyrosine degradation pathway. Deficiency of a similar gene in mouse causes oxidative stress. Several transcript variants of this gene encode multiple protein isoforms.

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100

Western blot analysis of GSTZ1 in mouse liver and HepG2 lysates using GSTZ1 antibody.

Immunohistochemistry analysis of paraffin-embedded Human cervical cancer using GSTZ1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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