CKAP4 (cytoskeleton-associated protein 4), also known as p63, CLIMP-63 or ERGIC-63, is a 602 amino acid single-pass type II transmembrane protein that links the endoplasmic reticulum (ER) to the cytoskeleton. Considered a novel protein in maintaining ER morphology, CKAP4 anchors the ER to microtubles which is required for maintaining ER spatial distribution during interphase of the cell cycle. CKAP4 can be reversibly palmitoylated and phosphorylated and is a major substrate of the palmitoyl acyltransferase, ZDHHC2.

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100

Western blot analysis of CKAP4 in 293T, hepG2, A549 lysates using CKAP4 antibody

Immunohistochemistry analysis of paraffin-embedded Human lung cancer using CKAP4 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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