The protein encoded by this gene belongs to the mitochondrial leucine/tyrosine/arginine motif family of proteins. Proteins of this family are short polypeptides that contain a leucine/tyrosine/arginine motif near the N-terminus. This gene is widely expressed with high levels in omental adipose tissue of obese individuals. In adipose tissue, the protein is localized to the nucleus where it promotes preadipocyte proliferation and lowers the rate of apoptosis to regulate adipose tissue homeostasis. Overexpression of this gene in adipocytes causes abnormal mitochondrial morphology and mitochondrial dysfunction. Alternative splicing results in multiple transcript variants.

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100

Western blot analysis of LYRM1 in mouse adipose lysates using LYRM1 antibody.

Immunohistochemistry analysis of paraffin-embedded Human tonsil using LYRM1 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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