The protein encoded by this gene belongs to the STEAP (six transmembrane epithelial antigen of prostate) family, and resides in the golgi apparatus. It functions as a metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+), using NAD(+) as acceptor. Studies in mice and human suggest that this gene maybe involved in adipocyte development and metabolism, and may contribute to the normal biology of the prostate cell, as well as prostate cancer progression. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100

Western blot analysis of STEAP4 in HepG2 lysates using STEAP4 antibody

Immunohistochemistry analysis of paraffin-embedded Human liver cancer using STEAP4 antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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