The protein encoded by this gene is a member of the purine/pyrimidine phosphoribosyltransferase family. It is a regulatory allosteric enzyme that catalyzes the first step of de novo purine nucleotide biosythetic pathway. This gene and PAICS/AIRC gene, a bifunctional enzyme catalyzing steps six and seven of this pathway, are located in close proximity on chromosome 4, and divergently transcribed from an intergenic region.
推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100

Western blot analysis of COASY in Hela, Raji, Jurkat, A549, NIH/3T3 lysates using COASY antibody

Immunohistochemistry analysis of paraffin-embedded Human brain using COASY antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
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