Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. It is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, which comprises the proton channel. The F1 complex consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled in a ratio of 3 alpha, 3 beta, and a single representative of the other 3. The Fo seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene encodes the e subunit of the Fo complex. Alternative splicing results in multiple transcript variants.

推荐稀释比 WB:1/500-1/1000;IHC:1/50-1/100

Western blot analysis of ATP5ME in Human heart, Human fetal liver, 293T, PC-3, Human liver lysates using ATP5ME antibody.

Immunohistochemistry analysis of paraffin-embedded Human colorectal cancer using ATP5ME antibody. High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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